Scientists report chemotherapy cocktail may cause adult women to grow new egg cells

Wednesday, December 7, 2016

Chemotherapy is usually associated with a collection of side effects ranging from digestive problems to hair loss, but a study published this week in Human Reproduction demonstrated that female cancer patients may find they have something in common with much younger women in one specific area — their ovaries.

Scientists from the University of Edinburgh examined donated ovarian tissue from fourteen female cancer patients, most of whom had Hodgkin lymphoma, and compared it to tissue from healthy women. They found the samples from women who had been treated with a specific chemotherapeutic regimen known as ABVD not only contained greater numbers of dormant ova — egg cells — than those from women treated with harsher regimens but also more than samples from healthy women. ABVD is named for combining several drugs known as adriamycin, bleomycin, vinblastine, and dacarbazine.

These reproductive cells were not merely more plentiful in ABVD patients. They also appeared immature, “new” in the words of lead researcher Evelyn Telfer. This challenges the conventional belief that girls are born with all the ova they will ever have and the numbers can only go down as the cells are either used up by the reproductive cycle or succumb to damage or natural aging. However, further research is needed to confirm this. The study covered relatively few patients by scientific standards, and David Albertini of the Center for Human Reproduction in New York has suggested the cells may not actually be freshly grown. Instead, they may have always been there and were merely rendered more detectable by ABVD treatment.

The ability to grow new egg cells may have significant implications for women in Western societies, many of whom postpone childbearing to establish careers, sometimes into their late thirties or forties. However, Telfer warns against making use of these findings too soon: “There’s so much we don’t know about the ovary. We have to be very cautious about jumping to clinical applications.”

The experiments had been discussed earlier this year at the annual conference of the European Society of Human Reproduction and Embryology.

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Canadian trio claim South Pole record for trans-Antarctic trip

Saturday, January 10, 2009

A trio of Canadian trekkers said Friday they completed the fastest unaided on-foot trek using the traditional route from Hercules Inlet on the Ronne Ice Shelf to the South Pole in a record time of 33 days, 23 hours and 30 minutes. Ottawa ultra-runner Ray Zahab, age 39, adventure journalist and architect Kevin Vallely, age 44, of Lynn Valley, North Vancouver and North Pole expeditionist Richard Weber, age 49, said they completed the 700-mile (1,130-kilometer) journey, at 10,000 feet altitude, finally arriving early Wednesday morning.

They endured a white-out but survived on a 7,000-calorie-a-day diet of pemmican, Gatorade drink powder, outdated salami, deep-fried bacon, cheese and butter. “If you took a cloud, wrapped it around your head and then duct-taped it, that’s what a white-out is like,” Mr Zahab, explained. The trio also suffered altitude sickness, vertigo, massive, painful blisters, and temperatures as low as minus 40. Zahab had to pull 170-lb (77-kg) sleds of equipment, traveling on foot and on snowshoes while the other two men skied.

According to ExplorersWeb.com’s founder, Tom Sjogren, the trio erased the previous record of 39 days, 7 hours and 49 minutes, which was set by American Todd Carmichael, the first American to cross Antarctica to the South Pole alone, on foot and with no assistance. He arrived at The Pole on December 21, 2008. “They have definitely broken the record,” said Sjogren. Guinness World Records spokesman, Damian Field, in London, however, said that “Guinness monitors a category for fastest unsupported trek to the South Pole, but it has no record currently listed.”

Prior to Carmichael, the record was held by Briton Hannah McKeand. In the fastest journey to the South Pole (600 nautical mile journey), she completed solo and in just 39 days, 9 hours and 33 minutes. In March 2008 she attempted to reach the North Pole alone and unsupported but had to abandon the trip after falling through the ice and badly damaging her shoulder.

Ray Zahab is a Canadian ultramarathon runner, personal trainer, and motivational speaker. He lives in Chelsea, Quebec, and is famous for his 4,300-mile (6,920-kilometer) epic run across the Sahara Desert in 2007, which was the subject of a documentary narrated by actor Matt Damon‘s “Running the Sahara.” He heads Impossible2Possible, a nonprofit organization which advocates planet protection. “I started looking at impossible places on the planet in the past year, and I said Antarctica is one of those impossible places, and if we can create an expedition, perhaps we can inspire a bunch of young people to realize they can achieve,’ Zahab said.

Richard Weber, M.S.M. (born June 9, 1959 in Edmonton, Alberta) is a world-renowned Canadian Arctic and polar adventurer, from Alcove (near Wakefield). From 1978 to 2006, he participated in, lead and organized more than 45 Arctic expeditions. Richard is the only person to have completed six full North Pole expeditions. He has therefore trekked to the North Pole more than anyone in history.

The trio were waiting out a storm before boarding a flight to Chile for Ottawa. “I’m pretty tired, actually,” said Kevin Vallely, calling from Patriot Hills, Antarctica. During the saga, Vallely was solely burdened with carrying the high-tech gear in his sled consisting of video cameras, satellite phones, hand-held computers, different kinds of solar panels, batteries and wires chargers. “Had we not brought all that stuff we probably would have got it done faster because we wouldn’t have had to carry all that weight, but then it doesn’t matter as much,” he explained. Vallely said he also intends to produce a documentary of the expedition.

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What To Expect From The Best Pet Supplies Store}

What to Expect from the Best Pet Supplies Store

by

Brian MillerIf this is the first time you own a pet, you probably do not really know too much about Pet Supplies or the stores where you can find all the products that you need, which means that you will need to do a bit of research before making any important decisions. After all, when talking about Pet Supplies Sydney, you need to think about the food, the toys, the beds and other accessories you might require for your pets. Make sure that you always pick quality supplies.You should expect the right Pet Supplies store to offer you a large variety of products for your pet. Let’s say that you own a dog and you have to buy everything it needs. This means that you have to look for food, for a leash, for a crate, for puppy training pads, for a kennel, for toys and even for a bed that you can keep indoors. As long as you come across a reliable shop, you should also have no trouble in coming across Pet Supplies Sydney for your pet, regardless if you are the owner of a cat, a dog, a rabbit, a hamster and so on. Of course, the list can go on and on. It all depends on what you think your pet needs or which of the existing products would be great for it. Now, when it comes to the range of dog food brands or beds that you can choose for your pet, the same Pet Supplies Sydney should offer you a few different options, not only based on budget, but also on the advantages that they have to offer. For instance, if you want to get your new puppy a regular bed that comes at an affordable price, you should be able to have this option if you visit a specific shop. However, if you are interested in a designer version, you should have this option as well.You should also expect the right Pet Supplies provider to offer you the option of ordering the products you need online with just a few short clicks. If you think about it, this is the best way of buying everything you need for your pet. As long as you come across a reliable shop, you should also have no trouble in coming across Pet Supplies Sydney for your pet, regardless if you are the owner of a cat, a dog, a rabbit, a hamster and so on.Maybe you own more than one pet and you need to buy food and other items for all of them. Wouldn’t it be easier if you could order it all from the same shop. This way, you do not have to worry about wasting too much time with this specific task. At the same time, you will most certainly manage to save up more money this way, especially if you visit the online store on a regular basis, looking for special deals.

If you are currently looking for the best possible

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Andrea Muizelaar on fashion, anorexia, and life after ‘Top Model’

Monday, November 26, 2007

In the 18 months since Andrea Muizelaar was crowned winner of the reality TV series Canada’s Next Top Model, her life has been a complete whirlwind. From working in a dollar store in her hometown of Whitby, Ontario, to modeling haute couture in Toronto, she had reached her dream of becoming a true Top Model.

But at what cost? Unknown to casual television viewers, Muizelaar had been enveloped in the eating disorder anorexia nervosa, which inevitably became too much for her to bear. She gave up modeling and moved back to Whitby, where she sought treatment for her disorder, re-entered college, and now works at a bank. Where is she now? Happy and healthy, she says.

Recently Andrea Muizelaar sat down with Wikinews reporter Mike Halterman in a candid interview that stretched to nearly two hours, as she told all about her hopes and aspirations, her battle with anorexia, and just what really happened on Canada’s Next Top Model.

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Loss of integrity in underground city tunnel causes evacuation of Downtown Montreal

Sunday, August 26, 2007

A one-inch settlement of the roof of The Bay tunnel to the Montreal Metro caused authorities to evacuate 12 blocks of the Montreal downtown core.

Several people noticed water infiltration in the tunnel over the last few days. On Friday, August 24, at 1 p.m., while investigating another water infiltration incident, The Bay employees noticed that the ceiling of the tunnel portion of The Bay’s basement sales area had descended one inch over a 7 meter length. They subsequently called police. The police and firefighters evacuated the basement of the downtown Bay store. The police closed de Maisonneuve Boulevard from Aylmer Street to Union Street, over the area of the crack.

At 4 p.m., firefighters evacuated the Parkade Montreal Building and The Bay Department Store after finding pieces of concrete falling from the Parkade Montreal structure, a multi-story carpark with five levels of offices on top. They also evacuated the downtown portion of the Line 1 / Green Line of the Montreal Metro subway, from Lionel-Groulx to Berri-UQAM stations, and evacuated the McGill metro station, which is situated below The Bay tunnel. After consulting with city engineers, Centre 2001, the loading dock of the Bay and its Hertz car rental agency, Les Promenades Cathedrale underground shopping centre and office tower, and a neighbouring office tower to the Parkade were also evacuated. Police cordoned off an area from Bleury Street in the east to University Street in the west, and from Ste-Catherine Street in the south to President Kennedy Street to the north.

The closure of the Metro caused havoc to the Friday afternoon rush hour, as over 40,000 people regularly use the Green Line (Line 1) every day. Montreal Transit Corporation workers issued directions during the day, though some may not have been informed of a provisionary bus service to replace the lost subway service. Loudspeakers announced that commuters should use the unaffected Orange Line (Line 2), which has lines between 5 and 10 blocks south of Line 1 (Green Line), and also connects to Lionel-Groulx and Berri-UQAM stations.

The downtown area is intended to remain closed for at least the weekend, along with portions of the underground city, or RESO. The tunnel was built in 1966. For the last few days, city work crews have been working above the slab in question, digging a one meter trench to install a median and segregate a new bike path on de Maisonneuve Boulevard. The tunnel roof lies five meters below street level.

Residents of Montreal are frustrated with the crumbling infrastructure in and around the city, including the collapse of the de la Concorde Boulevard overpass over Autoroute 19 expressway last year, the shattering of a column holding up the Autoroute 720 Ville Marie elevated expressway last month, and other incidents.

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Increase Storage By Adding An Island To Your Kitchen

Submitted by: Andreab Ball

You could also add an additional prep sink.

As you can see, when it comes to increasing your storage space, there’s nothing that your new designer kitchen island can’t do!

If you’re looking to give your kitchen that designer look and feel – not to mention the added bonus of extra storage space – then it’s time to add a gorgeous island to your kitchen.

Consider the kitchen island to be your secret storage weapon. While many homeowners like the added cooking space that an island provides, there’s a hidden bonus to the island that many of you may have overlooked:

[youtube]http://www.youtube.com/watch?v=F8BwFU52v_M[/youtube]

You can store virtually anything in these in-demand features. From extra pots and pans to large appliances, a kitchen island just might be what you need to free your kitchen from clutter.

And did we mention that a kitchen island is one of the most desirable features you can add to your kitchen?

Here are a few more tips on how to increase storage by adding an island to your kitchen:

? If you’ll be preparing food on your island, then be sure to install different food prep items to make the task easier. From cutting boards to utensil drawers, a kitchen island will store everything so that it’s on hand for dinnertime.

? Let’s face it – no one likes the look of a freestanding trash barrel. Put your island to good use by installing a pull-out trash drawer. It’s a simple way to increase storage as well as improve the aesthetic quality of your kitchen.

? Your kitchen island can provide a great space for you to install large appliances. You could install a cook top which will enable you to interact with your family and friends while preparing dinner. You could also add an additional prep sink.

As you can see, when it comes to increasing your storage space, there’s nothing that your new designer kitchen island can’t do!

The one area in most homes that sees the greatest amount activity is the kitchen. From preparing meals to entertaining guests, the kitchen is the heart of the home. A home with a spacious, well designed kitchen with plenty of storage and work space not only makes a home a more pleasant place to live but a home that has increased investment value. Any real estate agent will tell you that the design and condition of the kitchen can make or break a sale of a house. Kitchen remodeling or updating can be one of the best investments you will ever make in your home.

Updating a kitchen can give it a contemporary facelift. Today’s look includes durable granite countertops, modern cabinetry, and sleek stainless steel appliances. For kitchens that otherwise work well with convenient design, adequate storage space and counter space, updating can be a simple and cost-effective way to bring an entire home up to date. Updating can also offer additional convenience and organization with roll out shelving, spice racks, and easy, hidden trash access.

Open concept design is the most demanded floor plan among today’s homeowners and buyers. Kitchen remodeling can open up the wall between the kitchen and family living area to create that open space so ideal for family life and entertaining.

About the Author: Atlanta Kitchens supply top quality designer kitchen in Atlanta. We fit the very best in American Kitchen Design.

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Category:Jewellery

This is the category for jewellery.

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  • 8 April 2014: Scottish artist Alan Davie dies at age 93
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  • 6 September 2009: Man charged with attempted murder in £40 million London jewel heist
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Al Sharpton speaks out on race, rights and what bothers him about his critics

Monday, December 3, 2007

At Thanksgiving dinner David Shankbone told his white middle class family that he was to interview Reverend Al Sharpton that Saturday. The announcement caused an impassioned discussion about the civil rights leader’s work, the problems facing the black community and whether Sharpton helps or hurts his cause. Opinion was divided. “He’s an opportunist.” “He only stirs things up.” “Why do I always see his face when there’s a problem?”

Shankbone went to the National Action Network’s headquarters in Harlem with this Thanksgiving discussion to inform the conversation. Below is his interview with Al Sharpton on everything from Tawana Brawley, his purported feud with Barack Obama, criticism by influential African Americans such as Clarence Page, his experience running for President, to how he never expected he would see fifty (he is now 53). “People would say to me, ‘Now that I hear you, even if I disagree with you I don’t think you’re as bad as I thought,'” said Sharpton. “I would say, ‘Let me ask you a question: what was “bad as you thought”?’ And they couldn’t say. They don’t know why they think you’re bad, they just know you’re supposed to be bad because the right wing tells them you’re bad.”

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Don Brash, ex-leader of New Zealand National Party, leaves politics

Thursday, November 30, 2006

The ex-leader of New Zealand’s National Party, Dr Don Brash, has announced today that he has left his five year career in politics. Dr Brash had announced last week today that he was stepping down from leader of the National Party.

Dr. Brash was to stay on in politics as long as the new leader, John Key, gave him a senior portfolio and front bench position, where it was thought there would be no room for Dr Brash. However Dr Brash did not comment on whether he had sought that kind of position. The front bench positions and a possible portfolio reorganising will not be announced until tomorrow, Friday.

Over the past few days Dr Brash had been pondering his political career and he said that it is clear that he should leave politics after consulting with friends, colleagues and family including his wife, Je Lan. Dr Brash said: “I’ve come to the conclusion that now is the right time for me to leave Parliament and I informed John Key of that earlier today.”

At the press conference where he announced his intention to leave, few journalists were there compared to his resignation from leader conference.

Dr Brash will stay in Parliament until next year when he will not return. He said that he wanted to tie up loose knots.

Mr Key, last Thursday, said that he had only a few talks with Dr Brash, one on Tuesday and one this morning, but would not comment on Brash’s future. Dr Brash described those meetings as “constructive.”

When Dr Brash first entered politics in 2002 from being head of the Reserve Bank, he had wanted to make a difference and he said that he leaves with the belief that he had accomplished that. He also believes that National could take out the next election to be held in 2008 as it is in great shape. Dr Brash said: “I entered Parliament in 2002 with the intention of making a difference and I leave believing that I’ve done that. The National Party is in great shape to win the next election and I believe that debate about economic policy and about the Treaty is more mature and more realistic than it was five years ago.”

Dr Brash still claims that the book based around his leaked political emails by Nicky Hager, titled The Hollow Men: A Study in the Politics of Deception, played no part in his decision to leave.

Next year Katrina Shanks, accountant, will enter politics again to fill in the empty seat made by Dr Brash, she is currently at number 46 on the list. She had been in politics last year but was forced out after the special votes were counted. Ms Shanks said that she feels positive about changing her career but she said that she would have preferred entering politics on election night and not because Dr Brash had left.

Dr Brash announced that he will look into becoming a director at a company but would not be a director at a state owned enterprise, “not with this Government.” He told TV3’s Campbell Live programme that he will now look after his kiwifruit orchard.

Dr Brash said his colleagues reaction was mixed, Dr Brash said some said: “you’ve done a fantastic job for the National Party. Your work on that has finished.”

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Outsourced Accounting Services

Outsourced Accounting Services

by

orionshell

The word ‘outsource’ literally means hiring or engaging others to do your work effectively. If you want to stay tune to the competition, it is necessary to outsource certain things for better management ideas. Many companies have outsourced accounting and auditing to private parties so that they can concentrate on other major tasks of the organization.

[youtube]http://www.youtube.com/watch?v=T2QJisJMETQ[/youtube]

There are thousands of such accounting firms which offer professional service for reasonable cost. By hiring one of such companies, you can save considerable time which would otherwise be spent on the hassle of checking the accounts and balancing the sheet. The accounting firms are very dedicated in providing accurate service for their clients. They can stay in the market only if they offer continuous and timely service subject to the satisfaction of the client. The duties of the accounting firm include preparation of accounts annually and settling disputes of auditing, preparation of salary bill for the entire staff of the company and other pay roll service. Further outsourcing the accounts will free you from the hassle of filing returns annually. They would take care of filing income tax and sales tax return and even render help to the clients in the recovery of debts. They would also keep you updated with the future cash requirements in advance so that you are given sufficient time to make arrangement. Now some companies are handling their accounts efficiently with automation facility. But the desired output cannot be reached if there is complete automation. Sometimes these automated systems will not be able to match the needs of the company and again you are forced to do the method of standard accounting process by hand. To avoid this you can directly outsource the work of accounting to reputable companies and accountants who are expert in handling them. Initially the accounting firm would analyze the needs of your company making their service customer centric or highly customized. It is the duty of the accounting firm to provide timely service with well informed decisions about various aspects of accounts and handling cash. You can find out the best firm by doing analysis on the internet or alternatively you can ask opinion from similar companies like yours. Do not go for the company which offers outsourced accounting service for cheap rates since the very purpose of outsourcing will not be met. The firm you hire should be efficient and experience enough to handle the complete accounts of you and your company. The outsourcing has become trend for many organizations not only for accounts purpose but also for various other internal purposes like marketing their product etc. This conent has been taken from http://www.ideamarketers.com/?articleid=3236369&CFID=176195403&CFTOKEN=61267455

Mature yet progressive firm, DKS&S is dedicated to clients like you who want to grow their companies and accumulate personal net worth and

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