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Wednesday, March 23, 2011

By causing the mutation of one specific gene, researchers have produced mice with two frequently encountered behavioral traits of persons diagnosed with autism. Autism commonly affects the ability to interact socially and is associated with repetitive behavior. The finding was reported in the March 20 online edition of Nature.

Using mice, researchers at the Massachusetts Institute of Technology (MIT) and Duke University mutated one of the genes associated with autism, known as shank3, a gene that controls the production of the shank3 protein present in the brain. Mice that were given this mutation exhibited repetitive behavior and avoided social interactions with the mice around them.

According to MIT Professor Guoping Feng: “Our study demonstrated that Shank3 mutation in mice lead to defects in neuron-neuron communications.”

Shank3 protein are found in synapses within the brain. Synapses allow brain cells (called neurons) to communicate with each other. The mutation in the mouse gene interfered with this communication, apparently producing the subsequent autism-like traits. Researchers believe their work demonstrates the important role of shank3 in the functioning of brain circuits that determine behavior.

While hundreds of genes have been linked to autism in human patients, only a small percentage have been linked to shank3. Professor Feng hypothesizes that disruptions of other genes that act on the production of brain proteins affecting synaptic communication may also be related to autistic behavior. If this disruption is real, Feng claims that treatments could be developed to correct synaptic function for any defective synaptic protein in an autistic patient.

Feng continued; “These findings and the mouse model now allow us to figure out the precise neural circuit defects responsible for these abnormal behaviours, which could lead to novel strategies and targets for developing treatment.”

About one in 110 children in the U.S., and at least one in 100 in UK, have been diagnosed with an autism spectrum disorder, for which there is currently no effective cure.

Friday, April 13, 2007

New Zealand’s state-owned broadcaster, TVNZ (Television New Zealand) announced yesterday its proposed redundancy cuts that will see jobs go from various sectors, the most going from their news and current affairs sector.

At least 140 people will be told that they will be set to lose their job in the next six months, at least 50 of those are from the news sector.

Seven general reporting journalists will be leaving, which only leaves six left from the Auckland newsroom. Two sports reporting journalists will also be leaving from the Auckland newsroom, leaving six. Accredited parliament reporters also look to face redundancy cuts, as well as reporters from the Christchurch newsroom. As well as people losing their jobs, the Queenstown, Wanganui and Rotorua newsrooms will be closed, as well as the news reference library, and the current affairs show, Sunday looks set to close its Wellington office. Head of journalism at the University of Canterbury, Jim Tully says that the closing of the Queenstown newsroom is a big mistake. Current affairs show, Close Up will also lose two journalists and a Christchurch producer, but will gain a producer in Auckland. Fair Go, consumer affairs show, will lose three senior producers. Breakfast will lose a weather and sports presenter, and a producer.

The final decision of the exact numbers will be disclosed in the next few weeks, following consultation with the Engineering, Printing and Manufacturing Union, which represents, altogether, 5,000 employees.

Some of the job losses include experienced journalists, and Bill Ralston, former head of news and current affairs for TVNZ, said that they will be replaced by cheaper, inexperienced journalists. “If you do that your audience will reduce even further . . . this move makes no commercial sense whatsoever,” he said.

The Engineering, Printing and Manufacturing Union has described the job losses as an attack on democracy, and have launched a campaign titled, ‘Our Media’ to bring these issues to light. The National Secretary, Andrew Little has said that an essential function of communities is good quality regional news reporting, which will be reduced because of the job cuts.

Steve Maharey, broadcasting minister, has refused to comment regarding TVNZ.

Mr Ralston has said that this move will destroy TVNZ’s 30-year reputation being “…a good quality public broadcaster who gives you a news and current affairs service that you can believe and trust.”

He also questioned why they were cutting the news sector heavily when there are other sectors that are unnecessary, such as human resources. “Last time I looked at TVNZ it had 25 people in its human resources division – TV3 has none.” One TVNZ staff member has said that the job cuts were run by the human resources decision, and that they are very “anti-journalist”.

TVNZ plan to launch a new continuous news channel next year on New Zealand’s new digital platform, FreeView.

The New Zealand Herald is currently also looking at reducing staff numbers by outsourcing their sub-editors/copy editors.

Monday, August 27, 2012

London, England — As Paralympians ready for the Games which are set to open later this week, they have access to a world class fitness center inside the Paralympic Village which is designed to maximise their pre-Game preparations.

According to volunteers staffing the center, instead of being a single large room, as in Beijing, the building has numerous rooms. It, along with the adjacent Village Services Centre, is designed to be converted into a school after the games conclude. Rooms have been structured as a gym, an auditorium, and science laboratories.

Gym equipment is supplied by Technogym, an Italian firm that has supplied gym equipment for the Olympics since 2000. Equipment has been provided not just for for the Fitness Centre, but for gyms at all the Olympic venues. The newest equipment is oriented toward maximum flexibility, allowing athletes to exercise the particular muscles that they most require for their sport.

In addition to the equipment, the Fitness Centre also provides instructors trained in the use of the equipment, the likes of which athletes from many countries have never seen before. There are also a number of instructors available to provide motivational training.

Wednesday, August 3, 2005

The United States Department of Homeland Security (DHS) is deploying its new Homeland Security Information Network – Secret (HSIN-Secret) in all 50 state Emergency Operations Centers as well as 18 additional state and local law enforcement sites. “The secret network is a component of the HSIN, which is the primary conduit for DHS to share information on terrorist threats, suspicious activity and incident management with state, local, tribal and private-sector officials.” reports Government Computer News.

Development on this $350 million system by Northrop Grumman Corporation was begun in March of 2004 with basic operation achieved in just 4 months.

“The Homeland is more secure when each hometown is more secure,” said Secretary of Homeland Security Tom Ridge in DHS’s February 24, 2004 press release that launched the program. “Future program expansion will include the county level, communication at the classified SECRET level, and the involvement of the private sector.” it continues.

With the “Secret” component in place, classified information can now be disseminated to authorized individuals at all levels of government and business throughout the country almost instantly. HSIN lets most government agencies as well as many private companies doing business with the government share information on the whereabouts and suspicious activities of anyone that comes to their attention. Internal policies and the judgement of the system’s users provide privacy and civil rights protections, while who can access the system is determined by DHS.

Sunday, June 27, 2010

Toyota announced on Friday that it will recall around 17,000 Lexus vehicles in response to risks of the fuel tank in the cars leaking after a collision.

The Lexus HS 250h model was subjected to the recall following a US National Highway Traffic Safety Administration (NHTSA) investigation. Despite previously passing Toyota safety inspections, the conclusions of an NHTSA sub-contracted investigator were that; when the vehicles in question collided with an object at more than fifty-miles-per hour, more than 142 grams of fuel, the maximum allowed by US law, leaked from the crashed car.

According to Toyota, further tests did not show any additional failure of the fuel tank.

In response to the findings, Toyota issued a recall of all affected vehicles, since the company had no solution immediately available. The recall includes 13,000 cars already sold, as well as another 4,000 still at dealerships.

Toyota says it plans to conduct further tests to determine the cause of the leak. A Toyota spokesman, Brian Lyons, said that the company was “still working to determine what the root cause of the condition is.” It’s still unclear when exactly the recall will take place, or when dealerships will be allowed to sell this model again. Lyons said that Toyota is “working feverishly to get this resolved as soon as possible.”

Toyota isn’t aware of any accidents stemming from the leaking fuel tank in the affected vehicles, first introduced in the summer of 2009.

Monday, May 5, 2008

Computers and technology make our modern lifestyle more convenient, but they also create new risks like computer viruses and hacking. Many people want to enjoy the convenience of new technology, but they may not be aware of its problems.

WiMAX is being promoted in Taiwan by the Taipei Computer Association, the Industrial Technology Research Institute and the Ministry of Economic Affairs of the Republic of China. It is considered by some to be the communication standard for the next generation of mobile devices.

Information security companies are concerned increasingly by Internet crime, and some of them question the security of WiMAX. After all, everyone wants to welcome this new technology but is afraid of its potential to cause security issues.

Some companies have analyzed potential security issues which threaten the success of WiMAX. But what have they found?

Taking the opportunity of two press conferences in Taiwan, Wikinews Journalist Rico Shen briefly interviewed both Hsiao-wen Hung, President of Microsoft Research Asia and Li Chang, Deputy Secretary General of Taipei Computer Association. With their experience in the IT industry, they agreed to comment on this question.

Friday, March 10, 2006

On February 8, the same day Super Size Me opened in Prague, a Czech film company’s volunteer known as Karel Gustav Bozan began a 1 month diet of Czech pub food and beer in a Czech version called “Super Spek Me”; which translates loosely as “Super Flab Me”.

Zuzana Pudilova of Aerofilms described the volunteer at that time: “He is a well-built man between 45 and 50. He is almost 2 metres tall, he is not exactly thin but until now he has had quite a healthy lifestyle.”

Karel ate typical Czech pub food for an entire month with three rules: no vegetables or fresh fruit (unless they came with a meal) no exercise, and lots of beer.

Karel’s menu consisted entirely of typical Czech dishes. Obesity therapist, Iva Malkova, had warned at the beginning of the project: “People in the Czech Republic eat much more fat, especially animal fat than is recommended.” Pub meals in the Czech Republic often consist of such fatty items as goose with dumplings or sausages.

Yesterday the results were announced; Karel lost six kilos, his cholesterol went down and so did his liver enzymes, triglyceride and uric acid levels. His blood pressure did not change. At his interview with Radio Prague he said: “I feel good, great! The food was varied and there were even enough greens in the garnish. As for beer, I tried to alternate brands but I always settled it with Pilsner. I liked the experiment, it was all paid for by the distributor, Aerofilms. I would do it again, maybe they will propose it to me!”

Zuzana Pudilova of Aerofilms said: “The result of the experiment is surprising – both for us and the experts who monitored it. The medical report says our volunteer has lost weight and his blood sugar has dropped. So we have come to the conclusion that fatty Czech pub grub is not all that bad for you – which I guess wasn’t meant to be the result of the experiment at all.”

Friday, June 5, 2009

Data from the United States Labor Department says that the unemployment rate in the U.S. has reached its highest level in over 25 years, namely 9.4%.

The job loss rate, however, was only 345,000, which is the lowest monthly job loss rate since September of last year. Analysts had predicted that the loss could be as high as 525,000.

The news suggests that the US economy may be improving, as the job loss rate, which peaked at 741,000 jobs this January, has started to ease.

“Even as we see things start to stabilize and hopefully grow again, we do know that unemployment tends to lag, and so that the unemployment rate is going to be high and probably stay high for a while, precisely because that is sort of the normal pattern as we come out of recession,” said an economic adviser for the White House, Christina Romer.

Since the recession officially started in December 2007, the economy has shed over six million jobs, with 14.5 million residents now unemployed.

Tuesday, September 12, 2006

The upcoming 2006 Brampton municipal election, to be held November 13, features an array of candidates looking to represent their wards in city council or the council of the Peel Region.

Wikinews contributor Nick Moreau contacted many of the candidates, including Vicky Colbourne, asking them to answer common questions sent in an email. This ward’s incumbent is Paul Palleschi; also challenging Colbourne is David A. Esho and Curtis Grant.